Irinotecan (CPT-11) is a semisynthetic derivative of camptothecine that has proved activity in the treatment of colorectal carcinoma. The metabolites identiยฎed in humans include SN-38, SN-38 glucuronide, and several CYP3A-derived metabolites. We have studied the hepatic extraction, metabolism, and b
Moment analysis of stereoselective biliary excretion and chiral inversion of ketoprofen enantiomers in perfused rat liver
โ Scribed by Hiroyuki Yasui; Kiyoshi Yamaoka; Nobuhito Dote; Terumichi Nakagawa
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 515 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0022-3549
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