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Molybdenum-Mediated Carbonylation of Aryl Halides with Nucleophiles Using Microwave Irradiation

โœ Scribed by Roberts, Bryan; Liptrot, David; Alcaraz, Lilian; Luker, Tim; Stocks, Michael J.


Book ID
120364984
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
235 KB
Volume
12
Category
Article
ISSN
1523-7060

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Mo(CO) 6 acts as a source of carbon monoxide for the palladium-catalysed, microwave-assisted, carbonylative coupling of aryl or heteroaryl halides with sulfamide nucleophiles to yield aryl and heteroaryl acyl sulfamides.

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Palladium-catalyzed aminocarbonylations of various (hetero)aryl halides with allylamine using Mo(CO) 6 as a solid, in situ CO source, were explored. Microwave-enhanced conditions proved to be highly useful in promoting the conversions in a mere 10-20 min with various (hetero)aryl iodides, bromides a