We examined the genetic effect of DRD2 A1 allele in 167 Korean schizophrenics in relation to their smoking habit. Although there was no apparent difference in the genotype distributions of DRD2 gene among the female schizophrenics (n = 66), the male counterpart (n = 101) showed significant differenc
Molecular variation within the dopamine receptor DRD2 gene in migraine
β Scribed by Stephen J. Peroutka
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 44 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1129-2369
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A new biallelic polymorphism for FokI restriction enzyme due to C----T transition in the fourth intron of human DRD2 is described. It must be a usefull marker of this candidate gene for several mental disorders.
Polymorphism in intron I of the human dopamine D4 receptor is described.
## Abstract DRD~1~ and DRD~2~ receptor gene variants have been associated with clinical aspects of schizophrenia; however only specific features were analyzed in different samples. To assess the complex interaction between genetic and clinical factors, we studied the possible crossβinteractions bet