Presymptomatic genetic screening in fami
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A. Frilling; W. HΓΆppner; C. Eng; L. Mulligan; F. Raue; C. E. Broelsch
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Article
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1995
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Springer
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English
β 474 KB
Medullary thyroid carcinoma occurs sporadically or as a part of the inherited cancer syndrome multiple endocrine neoplasia (MEN) type 2. The MEN 2 gene has been identified as the RET proto-oncogene on chromosome 10. In MEN 2A, RET mutations are detectable in one of five cysteine codons within exons