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Molecular genetics of multiple endocrine neoplasia types 1 and 2

✍ Scribed by Marx, Stephen J.


Book ID
109947384
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
470 KB
Volume
5
Category
Article
ISSN
1474-1776

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Medullary thyroid carcinoma occurs sporadically or as a part of the inherited cancer syndrome multiple endocrine neoplasia (MEN) type 2. The MEN 2 gene has been identified as the RET proto-oncogene on chromosome 10. In MEN 2A, RET mutations are detectable in one of five cysteine codons within exons