Bladder cancer is one of the malignancies for which considerable information is available regarding molecular pathogenesis and genetic predictors of natural history, as well as response to treatment. Loss of heterozygosity of chromosome 9 appears to be essential to the genesis of superficial bladder
โฆ LIBER โฆ
Molecular targets and targeted therapies in bladder cancer management
โ Scribed by Ramy F. Youssef; Anirban P. Mitra; Georg Bartsch; Peter A. Jones; Donald G. Skinner; Richard J. Cote
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 469 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0724-4983
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## Abstract Here we review an approach to the design and production of antibody/ligand pairs for use in cell targeting procedures, to achieve functional affinity far greater than avidin/biotin. Using fundamental chemical principles, we have developed antibody/ligand pairs that retain the binding sp