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Molecular Phylogenetic Analysis of Zebra Finch Basic Helix-Loop-Helix Transcription Factors

โœ Scribed by Wuyi Liu; Chunjiang Zhao


Book ID
106362963
Publisher
Springer
Year
2010
Tongue
English
Weight
515 KB
Volume
49
Category
Article
ISSN
0006-2928

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HES-1 is a vertebrate homologue of the Drosophila basic helix-loop-helix (bHLH) protein Hairy, a transcriptional repressor that negatively regulates neuronal differentiation. HES-1 expression in neuronal precursors precedes and represses the expression of the neuronal commitment gene MASH-1, a bHLH