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Calcium/calmodulin inhibition of basic-helix-loop-helix transcription factor domains

✍ Scribed by Corneliussen, Brit; Holm, Magnus; Waltersson, Yvonne; Onions, Jacqueline; Hallberg, Bengt; Thornell, Anders; Grundström, Thomas

Book ID
109788352
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
777 KB
Volume
368
Category
Article
ISSN
0028-0836

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Cellular transcription factor E2F1 is thought to regulate the expression of genes important for cell cycle progression and cell proliferation. Deregulated E2F1 expression induces S-phase entry in quiescent cells and inhibits myogenic differentiation. We show here that E2F1 inhibits the activation of