𝔖 Bobbio Scriptorium
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Molecular models of cyclin-dependent kinase 1 complexed with inhibitors

✍ Scribed by Fernanda Canduri; Hugo Brandão Uchoa; Walter Filgueira de Azevedo Jr.

Book ID
116289257
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
565 KB
Volume
324
Category
Article
ISSN
0006-291X

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## Abstract The cyclin‐dependent kinases or CDKs participate in the regulation of both the cell progression cycle and the RNA polymerase‐II transcription cycle. In several human tumours deregulation of CDK‐related mechanisms have been detected, e.g., overexpression of cyclins or deletion of genes e