Polyploidization and regional gene duplication have occurred frequently during vertebrate evolution, providing the genetic material necessary for creating evolutionary novelties. Mammals, including man, can be regarded as diploid species with a polyploid history of evolution. Polyploidization steps
β¦ LIBER β¦
Molecular mechanisms regulating the tumor-targeting potential of splice-activated gene expression
β Scribed by Hayes, Gregory M; Dougherty, Shona T; Davis, Peter D; Dougherty, Graeme J
- Book ID
- 110019163
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 394 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0929-1903
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## Abstract Alterations of the Akt/mTOR pathway have been observed in numerous types of cancer, thus this pathway represents an exciting new target for molecular therapeutics. We investigated the expression of activated Akt (pβAkt) and mTOR (pβmTOR) in patients with adenocarcinoma of the cervix and