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Molecular Mechanisms of Vitamin D Action

✍ Scribed by Mark R. Haussler, G. Kerr Whitfield, Ichiro Kaneko…

Book ID: 120757618
Publisher: Springer
Year: 2012
Tongue: English
Weight: 977 KB
Volume: 92
Category: Article
ISSN: 1432-0827
DOI: 10.1007/s00223-012-9619-0

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## Abstract The biologically active metabolite of vitamin D, 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) is a secosteroid whose genomic mechanism of action is similar to that of other steroid hormones and is mediated by stereospecific interaction of 1,25(OH)~2~D~3~ with the vitamin D receptor (VDR