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Molecular Mechanisms of Thyroid Hormone Effects on Bone Growth and Function

โœ Scribed by Clare B. Harvey; Patrick J. O'Shea; Anthea J. Scott; Helen Robson; Thomas Siebler; Stephen M. Shalet; Jacques Samarut; Olivier Chassande; Graham R. Williams


Book ID
115639938
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
456 KB
Volume
75
Category
Article
ISSN
1096-7192

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## Abstract Excess thyroid hormone (TH) in adults causes osteoporosis and increases fracture risk. However, the mechanisms by which TH affects bone turnover are not elucidated. In particular, the roles of thyroid hormone receptor (TR) isotypes in the mediation of TH effects on osteoblastโ€mediated b