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Molecular mechanisms of tetrahydrobiopterin action on dopamine release in the striatum

โœ Scribed by Watanabe, Yumiko; Mataga, Nobuko; Ishihara, Takafumi; Noguchi, Teruhisa; Miwa, Souichi; Watanabe, Yasuyoshi

Book ID
123417302
Publisher
Elsevier Science
Year
1991
Weight
90 KB
Volume
14
Category
Article
ISSN
0921-8696

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Nicotinamide adenine dinucleotide (NADH) may be utilized for the synthesis and regeneration of tetrahydrobiopterin (BH 4 ), which in turn is an essential cofactor for tyrosine hydroxylase, the rate-limiting enzyme in the synthesis of dopamine (DA). NADH has been reported to relieve some of the sympt