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The regulation of dopamine release from striatum slices by tetrahydrobiopterin and l-arginine-derived nitric oxide

✍ Scribed by Li Ping Liang; Seymour Kaufman


Book ID
114004005
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
176 KB
Volume
800
Category
Article
ISSN
0006-8993

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## Abstract Hydroxylamine (0.01–30 mM), a nitric oxide (NO) generator, produced a concentration‐dependent release of [^3^H]dopamine ([^3^H]DA) from rat striatal slices. Hemoglobin (10 ΞΌM), a NO scavenger, reduced basal [^3^H]DA release and blocked hydroxylamine (100 ΞΌM)‐stimulated [^3^H]DA efflux.