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Molecular mechanisms of secondary imatinib resistance in patients with gastrointestinal stromal tumors

✍ Scribed by Chun-Meng Wang; Kai Huang; Ye Zhou; Chun-Yan Du; Yan-Wei Ye; Hong Fu; Xiao-Yan Zhou; Ying-Qiang Shi

Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
312 KB
Volume
136
Category
Article
ISSN
1432-1335

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## Abstract Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract. Long‐term survival of patients with metastatic disease has only been observed in patients with completely resected disease. Recently, the tyrosine kinase inhibitor imatinib has b