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Molecular mechanism of angiotensin II-induced insulin resistance in aortic vascular smooth muscle cells: Roles of Protein Tyrosine Phosphatase-1B

โœ Scribed by Pimonrat Ketsawatsomkron; David W. Stepp; David J. Fulton; Mario B. Marrero


Book ID
113952036
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
950 KB
Volume
53
Category
Article
ISSN
1537-1891

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## Abstract Angiotensin II is an octapeptide that regulates diverse cellular responses including the actin cytoskeletal organization. In this study, stable cell lines overexpressing wildโ€type or catalytically inactive SHPโ€2 were employed to elucidate the signaling pathway utilized by the SHPโ€2 tyro