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Molecular markers in gliomas: impact for the clinician

✍ Scribed by Silvia Hofer; Andrew B. Lassman


Book ID
107384395
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
192 KB
Volume
5
Category
Article
ISSN
1776-2596

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Loss of constitutional heterozygosity as determined through the analysis of restriction-fragment-length polymorphism (RFLP) on tumoral and constitutional DNA has proven to be helpful to delimit the location of tumor-suppressor genes in the human genome. In malignant gliomas this approach indicates t