Regional localization by in situ hybridi
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Elena Raimondi; Antonella Antonelli; Albert J. Driesel; Massimo Pandolfo
📂
Article
📅
1990
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Springer
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English
⚖ 345 KB
In order to determine the regional localization of the Friedreich's ataxia (FA) gene on chromosome 9, the DNA probe DR47 (D9S5), which detects a restriction fragment length polymorphism (RFLP) in tight linkage with the disease, was hybridized in situ to metaphase chromosomes. Our results enable the