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Molecular interactions of the intrinsic activation complex of coagulation: binding of native and activated human factors IX and X to defined phospholipid vesicles

โœ Scribed by Burri, Betty J.; Edgington, Thomas S.; Fair, Daryl S.


Book ID
120399637
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
861 KB
Volume
923
Category
Article
ISSN
0304-4165

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Blood coagulation factor X (FX) is converted to its active form (FXa) by a membrane bound multi-protein enzyme complex, comprised of factor VIII (FVIII), factor IXa (FIXa) and FX. Characterization of the molecular forces involved in the association of these proteins with phospholipids is crucial to