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Role of Activation of the Coagulation Factor VIII in Interaction with vWf, Phospholipid, and Functioning within the Factor Xase Complex

✍ Scribed by Evgueni L Saenko; Midori Shima; Andrey G Sarafanov


Book ID
114341888
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
292 KB
Volume
9
Category
Article
ISSN
1050-1738

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Blood coagulation factor X (FX) is converted to its active form (FXa) by a membrane bound multi-protein enzyme complex, comprised of factor VIII (FVIII), factor IXa (FIXa) and FX. Characterization of the molecular forces involved in the association of these proteins with phospholipids is crucial to