The generation of mice designed to overexpress activated forms of oncogenes or carrying targeted mutations in tumour suppressor genes, has allowed scientists to causally link the function of these genes with specific tumour processes, such as proliferation, apoptosis, angiogenesis or metastasis. In
β¦ LIBER β¦
Molecular insights into breast cancer from transgenic mouse models
β Scribed by Robert B. Dickson; Macro M. Gottardis; Glenn T. Merlino
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 744 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0265-9247
No coin nor oath required. For personal study only.
β¦ Synopsis
Breast oncogenes t genes Normal mechanisms of proliferation control by hormones and growth factors Fig. 1. Genetic and prolifcrativc factors iiitcract in susceptibility to and progression of breast cancer.
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