The generation of mice designed to overexpress activated forms of oncogenes or carrying targeted mutations in tumour suppressor genes, has allowed scientists to causally link the function of these genes with specific tumour processes, such as proliferation, apoptosis, angiogenesis or metastasis. In
โฆ LIBER โฆ
Mammary gland neoplasia: insights from transgenic mouse models
โ Scribed by Peter M. Siegel; William R. Hardy; William J. Muller
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 222 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0265-9247
No coin nor oath required. For personal study only.
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The transgenic mouse assay is now widely used for ent sources of variation in the data can be evaluthe study of mutagenesis in diverse rodent tissues ated in nested factorial experiments and treatment and to test chemicals for genotoxic potential. This effects can be assessed simultaneously. It avoi