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Molecular genotyping to predict debrisoquine hydroxylation phenotype

✍ Scribed by Daly, AnnK; Armstrong, Martin; Idle, JeffreyR

Book ID
123192262
Publisher
The Lancet
Year
1990
Tongue
English
Weight
320 KB
Volume
336
Category
Article
ISSN
0140-6736

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N-acetylation polymorphism is one of the representative pharmacogenetic traits that underlie interindividual and interethnic differences in response to xenobiotics. To develop a practical genotyping method to predict acetylator phenotype, we studied the conditions for accurate phenotyping, and ident