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Molecular genetics of urothelial malignancies: Mismatch repair genes as markers for detection and prognosis?

โœ Scribed by Fredrick S Leach

Book ID
117724152
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
330 KB
Volume
6
Category
Article
ISSN
1078-1439

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โœ Fredrick S. Leach; Jer-Tsong Hsieh; Kyle Molberg; M. Hossein Saboorian; John D. ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 224 KB ๐Ÿ‘ 2 views

## Background: The human mismatch repair (mmr) gene hmsh2 (human muts homolog-2) is a dna repair gene that has been reported to be mutated in 40% of hereditary nonpolyposis colon cancer (hnpcc) kindreds and a small percentage of sporadic tumors. hnpcc is a cancer predisposition syndrome with an inc