๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Molecular genetics of colorectal carcinoma

โœ Scribed by Stanley R. Hamilton


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
612 KB
Volume
70
Category
Article
ISSN
0008-543X

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Clinical impact of molecular genetic dia
โœ Henry T. Lynch; Patrice Watson; Trudy G. Shaw; Jane F. Lynch; Anne E. Harty; Bar ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 114 KB ๐Ÿ‘ 3 views

Hereditary nonpolyposis colorectal carcinoma (HNPCC) is the most common hereditary form of colorectal carcinoma (CRC) and may account for 5-10% of the total CRC burden. The discovery of DNA mismatch repair (MMR) genes, inclusive of hMSH2, hMLH1, hPMS2, and hMSH6, has enabled the identification of wh

The common molecular genetic alterations
โœ Brett R. Dix; Dr. Peter Robbins; Richie Soong; Deborah Jenner; Anthony K. House; ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 638 KB

Abbreviations: DCC, deleted in colon cancer (gene); MCC, mutated in colon cancer (gene); APC, adenomatous polyposis coli (gene); PCR, polymerase chain reaction; RFLP, restriction fragment length polymorphism; SSCP, single strand conformation polymorphism; ICC, immunocytochemistry; LOH, loss of heter

Molecular genetic evidence of the occurr
โœ John I. Risinger; J. Carl Barrett; Patrice Watson; Henry T. Lynch; Jeff Boyd ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 757 KB

## BACKGROUND. The hereditary nonpolyposis colorectal carcinoma (HNPCC) syndrome is an autosomal dominant genetic disorder caused by the inheritance of a mutation in one of a family of genes encoding DNA mismatch repair (MMR) proteins. HNPCC manifests as genetic instability in linked tumors. Clini