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Molecular genetic analysis of complete hydatidiform moles

✍ Scribed by Bruce W. Kovacs; Bejan Shahbahrami; David E. Tast; John P. Curtin


Book ID
119104983
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
993 KB
Volume
54
Category
Article
ISSN
0165-4608

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Familial biparental hydatidiform mole (FBHM) is a maternal-effect autosomal recessive disorder in which recurrent pregnancy failure with molar degeneration occurs. The phenotype mimics molar pregnancy due to androgenesis, despite the normal genetic makeup of the conceptus. FBHM appears to result fro