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Genetic analysis of repeated, biparental, diploid, hydatidiform moles

✍ Scribed by Lone Sunde; Lars O. Vejerslev; Mie P. Jensen; Søren Pedersen; Jens Michael Hertz; Lars Bolund

Book ID
119105874
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
693 KB
Volume
66
Category
Article
ISSN
0165-4608

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Familial biparental hydatidiform mole (FBHM) is a maternal-effect autosomal recessive disorder in which recurrent pregnancy failure with molar degeneration occurs. The phenotype mimics molar pregnancy due to androgenesis, despite the normal genetic makeup of the conceptus. FBHM appears to result fro