Although HBV has a circular DNA genome that is partially double stranded, it replicates by means of an RNA intermediate. The process is catalyzed by a translation product of the polymerase open reading frame that has reverse transcriptase activity. The enzyme is
Molecular evolution of the hepatitis B virus genome
β Scribed by Ziheng Yang; Ian J. Lauder; Hsiang Ju Lin
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 1010 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0022-2844
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
DNA recombinant technology has radically changed hepatitis B virus (HBV) virology. The genetic organization, the transcription and the replication of the virus are basically understood, structures of integrated HBV sequences in hepatocellular carcinoma have been characterized and new vaccines produc
## Abstract To investigate further the possible role of mutant hepatitis B viruses in the pathogenesis of fulminant hepatitis B, the genomic sequence of hepatitis B virus isolates from 9 South African blacks with this disease, including 5 entire genomes, was analysed. Seven of the isolates were gen
There are many factors leading to intrauterine infection with hepatitis B virus (HBV). These factors include viral structure, HBV mutations, HBV DNA level, placenta barrier, immune status of the mother, and susceptibility of the fetus. The purpose of this study was to investigate the possible relati
## Abstract Chronic hepatitis B infection is a major cause of hepatocellular cancer (HCC). The pathogenesis of the carcinogenesis is not fully understood. Viral proteins such as the X protein and the truncated middle S protein have been implicated to be transactivators. In order to investigate whet