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Molecular evidence for a positive role of Spt4 in transcription elongation

✍ Scribed by Rondon, A. G.

Book ID
111750167
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
258 KB
Volume
22
Category
Article
ISSN
0261-4189

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## Abstract **Background:** The human Spt4/Spt5 complex, termed DRB‐sensitivity inducing factor (DSIF) is a dual regulator of transcription that stimulates, or, when cooperating with negative elongation factor (NELF), represses RNA polymerase II (RNAPII) elongation. Spt4 and Spt5 are also thought t