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Core Structure of the Yeast Spt4-Spt5 Complex: A Conserved Module for Regulation of Transcription Elongation

✍ Scribed by Min Guo; Fei Xu; Jena Yamada; Thea Egelhofer; Yongxiang Gao; Grant A. Hartzog; Maikun Teng; Liwen Niu


Book ID
113918879
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
932 KB
Volume
16
Category
Article
ISSN
0969-2126

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Structure–function analysis of human Spt
✍ Dong-ki Kim; Naoto Inukai; Tomoko Yamada; Akiko Furuya; Hiroe Sato; Yuki Yamaguc 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 262 KB

## Abstract **Background:** The human Spt4/Spt5 complex, termed DRB‐sensitivity inducing factor (DSIF) is a dual regulator of transcription that stimulates, or, when cooperating with negative elongation factor (NELF), represses RNA polymerase II (RNAPII) elongation. Spt4 and Spt5 are also thought t