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Isolation of Murine SPT5 Homologue: Completion of the Isolation and Characterization of Human and Murine Homologues of Yeast Chromatin Structural Protein Complex SPT4, SPT5, and SPT6

โœ Scribed by Pei-Wen Chiang; Lisa Stubbs; Liang Zhang; David M. Kurnit


Book ID
115614175
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
134 KB
Volume
47
Category
Article
ISSN
0888-7543

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## Abstract **Background:** The human Spt4/Spt5 complex, termed DRBโ€sensitivity inducing factor (DSIF) is a dual regulator of transcription that stimulates, or, when cooperating with negative elongation factor (NELF), represses RNA polymerase II (RNAPII) elongation. Spt4 and Spt5 are also thought t