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Molecular dynamics simulations of a complex of HIV-1 protease and substrate: substrate-dependent efficiency of catalytic activity

✍ Scribed by N Okimoto; K Kitayama; M Hata; T Hoshino; M Tsuda


Book ID
114141409
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
280 KB
Volume
543
Category
Article
ISSN
0166-1280

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πŸ“œ SIMILAR VOLUMES


HIV-1 Protease Specificity Derived from
✍ D.B. Kassel; M.D. Green; R.S. Wehbie; R. Swanstrom; J. Berman πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 670 KB

A rapid and semiquantitative method is described for determining the relative \(k_{\mathrm{ca}} / K_{m}\) for individual peptides in defined substrate mixtures. The method utilizes electrospray ionization/mass spectrometry alone to semiquantitatively determine relative peptide substrate turnover rat