Molecular Diagnostics: Past, present, and future

✍ Scribed by Farid F. Chehab

• Publisher: John Wiley and Sons
• Year: 1993
• Tongue: English
• Weight: 683 KB
• Volume: 2
• Category: Article
• ISSN: 1059-7794
• DOI: 10.1002/humu.1380020502

✦ Synopsis

Molecular diagnostics (MDx) is currently a clinical reality that has its roots deep in the study of gene function, structure, and regulation. The multitude of human mutations identified in the various genetic diseases can now be assayed in the clinical molecular diagnostics laboratory. The polymerase chain reaction (PCR) has facilitated the transition from the research to the clinical laboratory, however, many methods which scan and identify known mutations may not be applicable in a clinical environment. A few of these methods are discussed and one technology that is well suited for clinical use is suggested. Well-trained personnel, regulation of MDx laboratories, and automation are a few of the requirements that will carry us into the promising future of molecular diagnosis.