We analyzed germline mutations of the BRCAl gene in 20 German breast/ovarian-cancer families. BRCA I mutations cosegregating with breast-cancer susceptibility were identified in 3 of these families. All mutations were found to generate a premature stop codon leading to the synthesis of truncated BRC
β¦ LIBER β¦
Molecular diagnosis methods of BRCA mutations in breast cancer
β Scribed by H. Rassi; N.G. Gorovenko; M. Houshmand; M.H. Sanati; M.H.H. Akbari
- Book ID
- 118624789
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 118 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1359-6349
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
BRCA1 mutations in German breast-cancer
β
Burkhard Jandrig; Klaus Grade; Susanne Seitz; Beate Waindzoch; Manuela MΓΌller; E
π
Article
π
1996
π
John Wiley and Sons
π
French
β 488 KB
π 2 views
BRCA1 and BRCA2 mutations in Russian fam
β
Irina V. Tereschenko; Victoria M. Basham; Bruce A.J. Ponder; Paul D.P. Pharoah
π
Article
π
2002
π
John Wiley and Sons
π
English
β 24 KB
π 2 views
We have screened index cases from 25 Russian breast/ovarian cancer families for germ-line mutations in all coding exons of the BRCA1 and BRCA2 genes, using multiplex heteroduplex analysis. In addition we tested 22 patients with breast cancer diagnosed before age 40 without family history and 6 patie
Breast-cancer risk in BRCA-mutation-nega
β
Hormuzd A Katki; Mitchell H Gail; Mark H Greene
π
Article
π
2007
π
The Lancet
π
English
β 42 KB
Family history, BRCA mutations and breas
β
OM Ginsburg; NV Dinh; TV To; LH Quang; ND Linh; BTH Duong; R Royer; M Llacuachaq
π
Article
π
2010
π
John Wiley and Sons
π
English
β 496 KB
Costs of breast cancer surveillance in B
β
Y.J.L. Kamm; C. Boetes; E.M.M. Adang; P. Bull; H.J. Bonenkamp; N. Hoogerbrugge
π
Article
π
2008
π
Elsevier Science
π
English
β 66 KB
BRCA1/BRCA2 Mutations and Breast Cancer
β
FRED GILBERT; MARY KAY DABNEY; KAREN DIEMER; SAMANTHA LUDWIG; GLADYS ROSENTHAL;
π
Article
π
1997
π
John Wiley and Sons
π
English
β 283 KB