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Molecular cytogenetic characterization of Philadelphia-negative rearrangements in chronic myeloid leukemia patients

✍ Scribed by Ayda Bennour; Hatem Bellâaj; Yosra Ben Youssef; Moez Elloumi; Abderrahim Khelif; Ali Saad; Halima Sennana


Book ID
106124460
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
526 KB
Volume
137
Category
Article
ISSN
1432-1335

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## Abstract ## BACKGROUND. Clonal cytogenetic abnormalities (CCA) were detected in Philadelphia chromosome (Ph)‐negative cells in some patients with chronic myeloid leukemia (CML) who attained a cytogenetic response to imatinib mesylate. In some patients, CCA/Ph‐negative status was associated with