Molecular biology techniques allow the unraveling of the genetic alterations that cause or accompany malignant disease. Since tumors are often heterogeneous, biochemical analysis of tissue homogenates is of limited diagnostic value. This paper gives examples of methods that are presently operational
Molecular cytogenetic analysis of two primary squamous cell carcinomas of the lung using multicolor fluorescence in situ hybridization
✍ Scribed by Bastian Gunawan; Masoud Mirzaie; Hans-Jürgen Schulten; Bärbel Heidrich; László Füzesi
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 219 KB
- Volume
- 439
- Category
- Article
- ISSN
- 1432-2307
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Background: Loss effecting the short arm of chromosome 3 occurs in nearly 60% of squamous cell carcinomas of the head and neck (scchn). karyotype analysis indicated that these losses occur in two regions, 3p13-p14 and 3p21-p24. to test these findings, we examined tumor dna from 38 scchn cell lin
We have previously generated an immortalized human fetal osteoblastic cell line (hFOB) using stably transfected temperature sensitive SV40 T-antigen (Harris et al. [1995a] J. Bone. Miner. Res. 10:178-1860). To characterize these cells for phenotypic/genotypic attributes desired for a good cell model
A notable degree of research attention is being focused on the use of fetal cells enriched from the blood of pregnant women as a non-invasive means of prenatal diagnosis. By using magnetic activated cells sorting (MACS) and ¯uorescence in situ hybridization (FISH), we have examined the ef®cacy of en