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Molecular cytogenetic analysis of the monoblastic cell line U937: karyotype clarification by G-banding, whole chromosome painting, microdissection and reverse painting, and comparative genomic hybridization

✍ Scribed by Ji-Yun Lee; Chul-Hoon Lee; Sung-Han Shim; Han-Kyu Seo; Jee-Hong Kyhm; Sechin Cho; Youl-Hee Cho


Book ID
114135375
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
343 KB
Volume
137
Category
Article
ISSN
0165-4608

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The immortalized, nontumorigenic human breast epithelial cell line HMT-3522 has been used as a model for premalignant and, eventually, malignant development. During cultivation, the karyotype evolution was followed. At an early stage, a very long constant phase showed a near-diploid karyotype, with