Complete cytogenetic characterization of the human breast cancer cell line MA11 combining G-banding, comparative genomic hybridization, multicolor fluorescence in situ hybridization, RxFISH, and chromosome-specific painting

Molecular cytogenetic analysis of a nont

Molecular cytogenetic analysis of a nontumorigenic human breast epithelial cell line that eventually turns tumorigenic: Validation of an analytical approach combining karyotyping, comparative genomic hybridization, chromosome painting, and single-locus fluorescence in situ hybridization

✍ Kirsten Vang Nielsen; Erik Niebuhr; Bent Ejlertsen; Søren Holstebroe; Mogens Win 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 219 KB 👁 2 views

The immortalized, nontumorigenic human breast epithelial cell line HMT-3522 has been used as a model for premalignant and, eventually, malignant development. During cultivation, the karyotype evolution was followed. At an early stage, a very long constant phase showed a near-diploid karyotype, with