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Molecular cytogenetic analysis of breast cancer: a combined multicolor fluorescence in situ hybridization and G-banding study of uncultured tumor cells

✍ Scribed by Angeliki D. Ferti; Maria J. Stamouli; Anna D. Panani; Sotirios A. Raptis; Bryan D. Young


Book ID
114135712
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
434 KB
Volume
149
Category
Article
ISSN
0165-4608

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The immortalized, nontumorigenic human breast epithelial cell line HMT-3522 has been used as a model for premalignant and, eventually, malignant development. During cultivation, the karyotype evolution was followed. At an early stage, a very long constant phase showed a near-diploid karyotype, with