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Molecular Crowding Stabilizes Folded RNA Structure by the Excluded Volume Effect

✍ Scribed by Kilburn, Duncan; Roh, Joon Ho; Guo, Liang; Briber, Robert M.; Woodson, Sarah A.

Book ID
124081252
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
984 KB
Volume
132
Category
Article
ISSN
0002-7863

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✍ Ariel FernΓ‘ndez πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier Science 🌐 English βš– 545 KB

We establish the role of excluded volume effects on the loss of conformational entropy due to pseudoknot formation in RNA. This pseudoknot appears to be the structural motif responsible for shaping the splicing site of certain noncoding RNA transcriptional products. Focusing on the illustrative exa