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Molecular connectivity study of halocarbon anesthetics

✍ Scribed by Thérèse Di Paolo; Lemont B. Kier; Lowell H. Hall


Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
442 KB
Volume
68
Category
Article
ISSN
0022-3549

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Molecular connectivity study of muscarin
✍ Lemont B. Kier; Lowell H. Hall 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 English ⚖ 539 KB

A correlation between three molecular connectivity indexes and the muscarinic receptor affinity of 104 acetylcholine antagonists was found. Analysis of structure from these indexes reveals not only the importance of the onium and the bulky portions of the molecule but also their virtual independence