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A study of monoalkylcarbamates as local anesthetics

✍ Scribed by Schlichting, D.A. ;Cwalina, G.E. ;Jenkins, G.L.

Publisher
Elsevier
Year
1950
Weight
275 KB
Volume
39
Category
Article
ISSN
0095-9553

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Isonipecaine, an isonipecotic acid derivative (l-methyl-4-phenylpiperidine-4-carboxylic acid ethyl ester hydrochloride), was found to possess considerable local anesthetic properties. I n the discussion of the results, the structural relationships of isonipecaine are compared with those of atropine,