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Molecular cloning of mevalonate pathway genes fromTaraxacum brevicorniculatumand functional characterisation of the key enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase

✍ Scribed by Nicole van Deenen; Anne-Lena Bachmann; Thomas Schmidt; Hubert Schaller; Jennifer Sand; Dirk Prüfer; Christian Schulze Gronover


Publisher
Springer
Year
2011
Tongue
English
Weight
1011 KB
Volume
39
Category
Article
ISSN
0301-4851

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We have used a cDNA clone for Chinese hamster 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase to isolate a genomic recombinant for human HMG-CoA reductase. The identity of the gene was confirmed by partial sequence analysis. Several unique fragments that will be useful for restriction frag