Molecular Cloning and Taste Bud-Specific Expression of a Novel Cyclic Nucleotide-Gated Channel
β Scribed by TAKUMI MISAKA; YUKO KUSAKABE; YASUFUMI EMORI; SOICHI ARAI; KEIKO ABEA
- Book ID
- 111394411
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 789 KB
- Volume
- 855
- Category
- Article
- ISSN
- 0890-6564
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We have cloned a novel voltage-gated K channel, LKv1, in two species of leech. The properties of LKv1 expressed in transiently transfected HEK293 cells is that of a delayed rectifier current. LKv1 may be a major modulator of excitability in leech neurons, since antibody localization studies show tha
The cyclic nucleotides cAMP and cGMP are important intracellular messengers involved in a wide variety of signal transduction events in the nervous system. It has been proposed that cAMP/cGMP elicit some of their effects through direct gating of a novel class of Ca 2Ο© -permeable ion channels that ar
Cyclic nucleotide-gated channels (CNGC) are ligand-gated ion channels that open and close in response to changes in the intracellular concentration of the second messengers, 3Π,5Π-cyclic adenosine monophosphate and 3Π,5Π-cyclic guanosine monophosphate. Most notably, they transduce the chemical signa