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Molecular cloning and sequence analysis of the sisomicin biosynthetic gene cluster fromMicromonospora

✍ Scribed by Wun-Rong Hong; Mei Ge; Zhi-Hong Zeng; Li Zhu; Min-Yu Luo; Lei Shao; Dai-Jie Chen

Publisher
Springer Netherlands
Year
2008
Tongue
English
Weight
278 KB
Volume
31
Category
Article
ISSN
0141-5492

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We have cloned and sequenced the Schizosaccharomyces pombe ade10 gene encoding 5-phosphoribosyl-4carboxamide 5-aminoimidazole transformylase inosine monophosphate cyclohydrolase. The sequence has an uninterrupted open reading frame of 1755 nucleotides corresponding to 585 amino acid residues. The de