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Molecular characterization of the P and I variants of α1-antitrypsin

✍ Scribed by Marco Seri; Barbara Magi; Carla Cellesi; Paolo M. Olia; Alessandra Renieri; Mario De Marchi


Book ID
110572650
Publisher
Springer
Year
1992
Tongue
English
Weight
454 KB
Volume
22
Category
Article
ISSN
0940-5437

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The molecular genetics of α1 antitrypsin
✍ Ying Wu; Richard C. Foreman 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 882 KB

The human serum protein u,-antitrypsin is the major source of antiprotease activity found in the blood. The protein is synthesised primarily by liver cells but, to a lesser extent, by at least one other cell type. Expression of the gene has provided a paradigm for studies on transcriptional regulati