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Expression, purification and characterization of recombinant Z α1-Antitrypsin—The most common cause of α1-Antitrypsin deficiency

✍ Scribed by Vita Levina; Weiwen Dai; Anja S. Knaupp; Dion Kaiserman; Mary C. Pearce; Lisa D. Cabrita; Phillip I. Bird; Stephen P. Bottomley

Book ID
116829015
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
626 KB
Volume
68
Category
Article
ISSN
1046-5928

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✍ E. K. Silverman; M. A. Province; E. J. Campbell; J. A. Pierce; D. C. Rao; N. G. 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 812 KB

## Louis a,-antitrypsin (a1 AT) deficiency is variably associated with the development of pulmonary emphysema. To gain insight into the process which begins the Z point mutation at the Protease Inhibitor (Pi) locus and results in the variable development of emphysema, three quantitative phenotypes