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Molecular characteristics of the intron 22 homologs of the coagulation factor VIII gene: an update

โœ Scribed by C. D. DE BRASI; D. J. BOWEN


Book ID
109152653
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
125 KB
Volume
6
Category
Article
ISSN
1538-7933

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MspI polymorphic site in intron 22 of th
โœ Hiroshi Inaba; Michio Fujimaki; Haig H. Kazazian; Stylianos E. Antonarakis ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer ๐ŸŒ English โš– 112 KB

A novel MspI DNA polymorphic site has been found in intron 22 of the human factor VIII gene. This site is informative almost exclusively in the Japanese population (heterozygosity 0.45) and will be of considerable importance in carrier detection and prenatal diagnosis of hemophilia A in this populat