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Molecular biomarkers of resistance to anti-EGFR treatment in metastatic colorectal cancer, from classical to innovation

✍ Scribed by Giampieri, Riccardo; Scartozzi, Mario; Del Prete, Michela; Maccaroni, Elena; Bittoni, Alessandro; Faloppi, Luca; Bianconi, Maristella; Cecchini, Luca; Cascinu, Stefano

Book ID
122866649
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
985 KB
Volume
88
Category
Article
ISSN
1040-8428

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## Abstract Colorectal cancer is the third most common cancer with a 5‐year survival rate of less than 10%. It is caused by alterations of multiple signal pathways which are affected by both genetic and environmental factors. In some cases, EGFR is important in the carcinogenesis of colorectal canc