✦ LIBER ✦

Molecular biology of T-cell-derived lymphokines: A model system for proliferation and differentiation of hemopoietic cells

✍ Scribed by K. Arai; T. Yokota; A. Miyajima; N. Arai; F. Lee

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 682 KB
Volume: 5
Category: Article
ISSN: 0265-9247
DOI: 10.1002/bies.950050407

No coin nor oath required. For personal study only.

✦ Synopsis

Many lymphokine genes have now been cloned from activated T cells and their products have been expressed in mammalian cells. Use of these recombinant lymphokines has provided the opportunity to evaluate both the spectrum of their biological activities and the mechanisms of their action in promoting proliferation and diflerentiation of hemopoietic and lymphoid cells. Characterization of the structure of lymphokine genes willprovide information about their regulated expression in T-cell activation.

29 NISHIZUKA, Y. (1984). The role of protein kinase C in cell surface signal transduction and tumor promotion. Nature 308,693-697. 30 ISHIKAWA, T., UNO, I. & MATSUMOTO, K. (1986). The role of CAMP in controlling yeast cell division. BioEssays 4, 52-56.

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